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Perfusion Pressure Is a Critical Determinant of the Intratumoral Extravasation of Oncolytic Viruses
Antitumor efficacy of oncolytic virotherapy is determined by the density and distribution of infectious centers within the tumor, which may be heavily influenced by the permeability and blood flow in tumor microvessels. Here, we investigated whether systemic perfusion pressure, a key driver of tumor...
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| Publicado no: | Mol Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817823/ https://ncbi.nlm.nih.gov/pubmed/26647825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.219 |
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