Overcoming cancer cell resistance to VSV oncolysis with JAK1/2 inhibitors

Oncolytic vesicular stomatitis virus (VSV) has potent antitumor activity but some cancer cells are resistant to VSV killing, either constitutively or due to type I interferon (IFN) inducing an antiviral state in the cells. Here, we evaluated VSV oncolysis of a panel of human head and neck cancer cel...

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Publicado en:Cancer Gene Ther
Autores principales: Escobar-Zarate, D, Liu, Y-P, Suksanpaisan, L, Russell, SJ, Peng, K-W
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817541/
https://ncbi.nlm.nih.gov/pubmed/24030211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2013.55
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