Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation

The mold Aspergillus fumigatus causes invasive infection in immunocompromised patients. Recently, galactosaminogalactan (GAG), an exopolysaccharide composed of galactose and N-acetylgalactosamine (GalNAc), was identified as a virulence factor required for biofilm formation. The molecular mechanisms...

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Udgivet i:mBio
Main Authors: Lee, Mark J., Geller, Alexander M., Bamford, Natalie C., Liu, Hong, Gravelat, Fabrice N., Snarr, Brendan D., Le Mauff, François, Chabot, Joseé, Ralph, Benjamin, Ostapska, Hanna, Lehoux, Mélanie, Cerone, Robert P., Baptista, Stephanie D., Vinogradov, Evgeny, Stajich, Jason E., Filler, Scott G., Howell, P. Lynne, Sheppard, Donald C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817252/
https://ncbi.nlm.nih.gov/pubmed/27048799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00252-16
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