Small Intestine but Not Liver Lysophosphatidylcholine Acyltransferase 3 (Lpcat3) Deficiency Has a Dominant Effect on Plasma Lipid Metabolism

Lysophosphatidylcholine acyltransferase 3 (Lpcat3) is involved in phosphatidylcholine remodeling in the small intestine and liver. We investigated lipid metabolism in inducible intestine-specific and liver-specific Lpcat3 gene knock-out mice. We produced Lpcat3-Flox/villin-Cre-ER(T2) mice, which wer...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Kabir, Inamul, Li, Zhiqiang, Bui, Hai H., Kuo, Ming-Shang, Gao, Guangping, Jiang, Xian-Cheng
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Lipids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817191/
https://ncbi.nlm.nih.gov/pubmed/26828064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.697011
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