Non-Carriers of Reduced-Function CYP2C19 Alleles are Most Susceptible to Impairment of the Anti-Platelet Effect of Clopidogrel by Proton-Pump Inhibitors: A Pilot Study

BACKGROUND: The phenomenon of CYP2C19 polymorphism affects the metabolism of both clopidogrel and proton-pump inhibitors (PPI). However, concomitant use of both drugs may reduce the desired therapeutic effects. In this study, we evaluated whether individuals with different numbers of reduced-functio...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Acta Cardiol Sin
Huvudupphovsmän: Lee, Jen-Kuang, Wu, Cho-Kai, Juang, Jyh-Ming, Tsai, Chia-Ti, Hwang, Juey-Jen, Lin, Jiuun-Lee, Chiang, Fu-Tien
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taiwan Society of Cardiology 2016
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816920/
https://ncbi.nlm.nih.gov/pubmed/27122952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6515/ACS20160201A
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk