Mechanisms for Two-Step Proton Transfer Reactions in the Outward-Facing Form of MATE Transporter

Bacterial pathogens or cancer cells can acquire multidrug resistance, which causes serious clinical problems. In cells with multidrug resistance, various drugs or antibiotics are extruded across the cell membrane by multidrug transporters. The multidrug and toxic compound extrusion (MATE) transporte...

Full description

Saved in:
Bibliographic Details
Published in:Biophys J
Main Authors: Nishima, Wataru, Mizukami, Wataru, Tanaka, Yoshiki, Ishitani, Ryuichiro, Nureki, Osamu, Sugita, Yuji
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2016
Subjects:
Channels and Transporters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816688/
https://ncbi.nlm.nih.gov/pubmed/27028644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.01.027
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items