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Mechanisms and Consequences of eNOS Dysfunction in Hypertension

Reduced nitric oxide (NO) bioavailability contributes to endothelial dysfunction and hypertension. The endothelial isoform of NO synthase (eNOS) is responsible for the production of NO within endothelium. Loss of eNOS cofactor tetrahydrobiopterin to initial increase in oxidative stress leads to unco...

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Bibliographic Details
Published in:J Hypertens
Main Authors: Li, Qiang, Yon, Ji-Youn, Cai, Hua
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816601/
https://ncbi.nlm.nih.gov/pubmed/25882860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000000587
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