Critical Endothelial Regulation by LRP5 during Retinal Vascular Development

Vascular abnormalities in the eye are the leading cause of many forms of inherited and acquired human blindness. Loss-of-function mutations in the Wnt-binding co-receptor LRP5 leads to aberrant ocular vascularization and loss of vision in genetic disorders such as osteoporosis-pseudoglioma syndrome....

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Publicat a:PLoS One
Autors principals: Huang, Wei, Li, Qing, Amiry-Moghaddam, Mahmood, Hokama, Madoka, Sardi, Sylvia H., Nagao, Masashi, Warman, Matthew L., Olsen, Bjorn R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816525/
https://ncbi.nlm.nih.gov/pubmed/27031698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152833
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