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Clinical MRSA isolates from skin and soft tissue infections show increased in vitro production of phenol soluble modulins

BACKGROUND: Phenol-soluble modulins (PSMs) are amphipathic, pro-inflammatory proteins secreted by most Staphylococcus aureus isolates. This study tested the hypothesis that in vitro PSM production levels are associated with specific clinical phenotypes. METHODS: 177 methicillin-resistant S. aureus (...

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Detalhes bibliográficos
Publicado no:J Infect
Main Authors: Berlon, Nicholas R., Qi, Robert, Sharma-Kuinkel, Batu K., Joo, Hwang-Soo, Park, Lawrence P., George, Dennis, Thaden, Joshua T., Messina, Julia A., Maskarinec, Stacey A., Mueller-Premru, Manica, Athan, Eugene, Tattevin, Pierre, Pericas, Juan M., Woods, Christopher W., Otto, Michael, Fowler, Vance G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816458/
https://ncbi.nlm.nih.gov/pubmed/26079275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinf.2015.06.005
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