Increased In Vitro Phenol-Soluble Modulin Production is Associated with Soft Tissue Infection Source in Clinical Isolates of Methicillin-Susceptible Staphylococcus aureus

BACKGROUND: Phenol-soluble modulins (PSM) are amphipathic proteins produced by Staphylococcus aureus that promote virulence, inflammatory response, and biofilm formation. We previously showed that MRSA isolates from soft tissue infection (SSTI) produced significantly higher levels of PSM than MRSA i...

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Detalhes bibliográficos
Publicado no:J Infect
Main Authors: Qi, Robert, Joo, Hwang-Soo, Sharma-Kuinkel, Batu, Berlon, Nicholas R., Park, Lawrence, Fu, Chih-lung, Messina, Julia A., Thaden, Joshua T., Yan, Qin, Ruffin, Felicia, Maskarinec, Stacey, Warren, Bobby, Chu, Vivian H., Fortes, Claudio Q., Giannitsioti, Efthymia, Durante-Mangoni, Emanuele, Kanafani, Zeina A., Otto, Michael, Fowler, Vance G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761485/
https://ncbi.nlm.nih.gov/pubmed/26778460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinf.2015.11.002
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