Increased In Vitro Phenol-Soluble Modulin Production is Associated with Soft Tissue Infection Source in Clinical Isolates of Methicillin-Susceptible Staphylococcus aureus

BACKGROUND: Phenol-soluble modulins (PSM) are amphipathic proteins produced by Staphylococcus aureus that promote virulence, inflammatory response, and biofilm formation. We previously showed that MRSA isolates from soft tissue infection (SSTI) produced significantly higher levels of PSM than MRSA i...

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Bibliografske podrobnosti
izdano v:J Infect
Main Authors: Qi, Robert, Joo, Hwang-Soo, Sharma-Kuinkel, Batu, Berlon, Nicholas R., Park, Lawrence, Fu, Chih-lung, Messina, Julia A., Thaden, Joshua T., Yan, Qin, Ruffin, Felicia, Maskarinec, Stacey, Warren, Bobby, Chu, Vivian H., Fortes, Claudio Q., Giannitsioti, Efthymia, Durante-Mangoni, Emanuele, Kanafani, Zeina A., Otto, Michael, Fowler, Vance G.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761485/
https://ncbi.nlm.nih.gov/pubmed/26778460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinf.2015.11.002
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