Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199

Human embryonic stem cells (hESCs) are hypersensitive to genotoxic stress and display lower survival ability relative to their differentiated progeny. Herein, we attempted to investigate the source of this difference by comparing the DNA damage responses triggered by the topoisomerase I inhibitor ca...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: García, Carolina Paola, Videla Richardson, Guillermo Agustín, Dimopoulos, Nicolás Alexis, Fernandez Espinosa, Damián Darío, Miriuka, Santiago Gabriel, Sevlever, Gustavo Emilio, Romorini, Leonardo, Scassa, María Elida
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816327/
https://ncbi.nlm.nih.gov/pubmed/27030982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152607
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