Effects of neferine on Kv4.3 channels expressed in HEK293 cells and ex vivo electrophysiology of rabbit hearts

AIM: Neferine is an isoquinoline alkaloid isolated from seed embryos of Nelumbo nucifera (Gaertn), which has a variety of biological activities. In this study we examined the effects of neferine on Kv4.3 channels, a major contributor to the transient outward current (I(to)) in rabbit heart, and on e...

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Bibliografiske detaljer
Udgivet i:Acta Pharmacol Sin
Main Authors: Wang, Chen, Chen, Yu-fang, Quan, Xiao-qing, Wang, Huan, Zhang, Rui, Xiao, Jun-hua, Wang, Jia-ling, Zhang, Cun-tai, Xiang, Ji-zhou, Tang, Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816235/
https://ncbi.nlm.nih.gov/pubmed/26592512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.83
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