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Dihydropyridine Ca(2+) channel antagonists and agonists block Kv4.2, Kv4.3 and Kv1.4 K(+) channels expressed in HEK293 cells
1. We have determined the molecular basis of nicardipine-induced block of cardiac transient outward K(+) currents (I(to)). Inhibition of I(to) was studied using cloned voltage-dependent K(+) channels (Kv) channels, rat Kv4.3L, Kv4.2, and Kv1.4, expressed in human embryonic kindey cell line 293 (HEK2...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573880/ https://ncbi.nlm.nih.gov/pubmed/12788813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705281 |
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