Pdcd4 deficiency enhances macrophage lipoautophagy and attenuates foam cell formation and atherosclerosis in mice

Macrophage foam cells, a major component of the atherosclerotic lesion, have vital roles in the development of atherosclerosis. Lipoautophagy, a type of autophagy characterized by selective delivery of lipid droplet for lysosomal degradation, may impact atherosclerosis by regulating macrophage foam...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, L, Jiang, Y, Song, X, Guo, C, Zhu, F, Wang, X, Wang, Q, Shi, Y, Wang, J, Gao, F, Zhao, W, Chen, Y H, Zhang, L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816189/
https://ncbi.nlm.nih.gov/pubmed/26775706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.416
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