GADD45B mediates podocyte injury in zebrafish by activating the ROS-GADD45B-p38 pathway

GADD45 gene has been implicated in cell cycle arrest, cell survival or apoptosis in a cell type specific and context-dependent manner. Members of GADD45 gene family have been found differentially expressed in several podocyte injury models, but their roles in podocytes are unclear. Using an in vivo...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Chen, Z, Wan, X, Hou, Q, Shi, S, Wang, L, Chen, P, Zhu, X, Zeng, C, Qin, W, Zhou, W, Liu, Z
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816163/
https://ncbi.nlm.nih.gov/pubmed/26794661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.300
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