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Triptolide attenuates proteinuria and podocyte apoptosis via inhibition of NF-κB/GADD45B
Podocyte injury is a primary contributor to proteinuria. Triptolide is a major active component of Tripterygium wilfordii Hook F that exhibits potent antiproteinuric effects. We used our previously developed in vivo zebrafish model of inducible podocyte-target injury and found that triptolide treatm...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6052061/ https://ncbi.nlm.nih.gov/pubmed/30022148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29203-1 |
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