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Multiple amino acid sensing inputs to mTORC1
The evolutionarily conserved target of rapamycin complex 1 (TORC1) is a master regulator of cell growth and metabolism. In mammals, growth factors and cellular energy stimulate mTORC1 activity through inhibition of the TSC complex (TSC1-TSC2-TBC1D7), a negative regulator of mTORC1. Amino acids signa...
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| 出版年: | Cell Res |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816134/ https://ncbi.nlm.nih.gov/pubmed/26658722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.146 |
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