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The function of Drosophila p53 isoforms in apoptosis

The p53 protein is a major mediator of the cellular response to genotoxic stress and is a crucial suppressor of tumor formation. In a variety of organisms, p53 and its paralogs, p63 and p73, each encode multiple protein isoforms through alternative splicing, promoters, and translation start sites. T...

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Détails bibliographiques
Publié dans:Cell Death Differ
Auteurs principaux: Zhang, B, Rotelli, M, Dixon, M, Calvi, B R
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816103/
https://ncbi.nlm.nih.gov/pubmed/25882045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.40
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