MYB controls erythroid versus megakaryocyte lineage fate decision through the miR-486-3p-mediated downregulation of MAF

The transcription factor MYB has a key role in hematopoietic progenitor cells (HPCs) lineage choice, by enhancing erythropoiesis at the expense of megakaryopoiesis. We previously demonstrated that MYB controls erythroid versus megakaryocyte lineage decision by transactivating KLF1 and LMO2 expressio...

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Publicat a:Cell Death Differ
Autors principals: Bianchi, E, Bulgarelli, J, Ruberti, S, Rontauroli, S, Sacchi, G, Norfo, R, Pennucci, V, Zini, R, Salati, S, Prudente, Z, Ferrari, S, Manfredini, R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816102/
https://ncbi.nlm.nih.gov/pubmed/25857263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.30
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