MYB controls erythroid versus megakaryocyte lineage fate decision through the miR-486-3p-mediated downregulation of MAF

The transcription factor MYB has a key role in hematopoietic progenitor cells (HPCs) lineage choice, by enhancing erythropoiesis at the expense of megakaryopoiesis. We previously demonstrated that MYB controls erythroid versus megakaryocyte lineage decision by transactivating KLF1 and LMO2 expressio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Bianchi, E, Bulgarelli, J, Ruberti, S, Rontauroli, S, Sacchi, G, Norfo, R, Pennucci, V, Zini, R, Salati, S, Prudente, Z, Ferrari, S, Manfredini, R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816102/
https://ncbi.nlm.nih.gov/pubmed/25857263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.30
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