Polygenic susceptibility to testicular cancer: implications for personalised health care

BACKGROUND: The increasing incidence of testicular germ cell tumour (TGCT) combined with its strong heritable basis suggests that stratified screening for the early detection of TGCT may be clinically useful. We modelled the efficiency of such a personalised screening approach, based on genetic risk...

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Bibliografische gegevens
Gepubliceerd in:Br J Cancer
Hoofdauteurs: Litchfield, Kevin, Mitchell, Jonathan S, Shipley, Janet, Huddart, Robert, Rajpert-De Meyts, Ewa, Skakkebæk, Niels E, Houlston, Richard S, Turnbull, Clare
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
Onderwerpen:
Genetics & Genomics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815881/
https://ncbi.nlm.nih.gov/pubmed/26461055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.334
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