Polygenic susceptibility to testicular cancer: implications for personalised health care

BACKGROUND: The increasing incidence of testicular germ cell tumour (TGCT) combined with its strong heritable basis suggests that stratified screening for the early detection of TGCT may be clinically useful. We modelled the efficiency of such a personalised screening approach, based on genetic risk...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Litchfield, Kevin, Mitchell, Jonathan S, Shipley, Janet, Huddart, Robert, Rajpert-De Meyts, Ewa, Skakkebæk, Niels E, Houlston, Richard S, Turnbull, Clare
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Genetics & Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815881/
https://ncbi.nlm.nih.gov/pubmed/26461055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.334
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