Polygenic susceptibility to testicular cancer: implications for personalised health care

BACKGROUND: The increasing incidence of testicular germ cell tumour (TGCT) combined with its strong heritable basis suggests that stratified screening for the early detection of TGCT may be clinically useful. We modelled the efficiency of such a personalised screening approach, based on genetic risk...

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Bibliographic Details
Published in:Br J Cancer
Main Authors: Litchfield, Kevin, Mitchell, Jonathan S, Shipley, Janet, Huddart, Robert, Rajpert-De Meyts, Ewa, Skakkebæk, Niels E, Houlston, Richard S, Turnbull, Clare
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
Subjects:
Genetics & Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815881/
https://ncbi.nlm.nih.gov/pubmed/26461055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.334
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