Polygenic susceptibility to testicular cancer: implications for personalised health care

BACKGROUND: The increasing incidence of testicular germ cell tumour (TGCT) combined with its strong heritable basis suggests that stratified screening for the early detection of TGCT may be clinically useful. We modelled the efficiency of such a personalised screening approach, based on genetic risk...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Cancer
Prif Awduron: Litchfield, Kevin, Mitchell, Jonathan S, Shipley, Janet, Huddart, Robert, Rajpert-De Meyts, Ewa, Skakkebæk, Niels E, Houlston, Richard S, Turnbull, Clare
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Genetics & Genomics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815881/
https://ncbi.nlm.nih.gov/pubmed/26461055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.334
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