Molecular targets for anticancer redox chemotherapy and cisplatin-induced ototoxicity: the role of curcumin on pSTAT3 and Nrf-2 signalling

BACKGROUND: In oncology, an emerging paradigm emphasises molecularly targeted approaches for cancer prevention and therapy and the use of adjuvant chemotherapeutics to overcome cisplatin limitations. Owing to their safe use, some polyphenols, such as curcumin, modulate important pathways or molecula...

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Опубликовано в: :Br J Cancer
Главные авторы: Fetoni, A R, Paciello, F, Mezzogori, D, Rolesi, R, Eramo, S L M, Paludetti, G, Troiani, D
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
Предметы:
Translational Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815880/
https://ncbi.nlm.nih.gov/pubmed/26469832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.359
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