Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer

BACKGROUND: Oestrogen receptor-negative (ER−) breast cancer is intrinsically sensitive to chemotherapy. However, tumour response is often incomplete, and relapse occurs with high frequency. The aim of this work was to analyse the molecular characteristics of residual tumours and early response to ch...

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Dettagli Bibliografici
Pubblicato in:Br J Cancer
Autori principali: Legrier, Marie-Emmanuelle, Bièche, Ivan, Gaston, Julie, Beurdeley, Arnaud, Yvonnet, Vanessa, Déas, Olivier, Thuleau, Aurélie, Château-Joubert, Sophie, Servely, Jean-Luc, Vacher, Sophie, Lassalle, Myriam, Depil, Stéphane, C Tucker, Gordon, Fontaine, Jean-Jacques, Poupon, Marie-France, Roman-Roman, Sergio, Judde, Jean-Gabriel, Decaudin, Didier, Cairo, Stefano, Marangoni, Elisabetta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
Soggetti:
Translational Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815803/
https://ncbi.nlm.nih.gov/pubmed/26695443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.398
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