PKD1 is a potential biomarker and therapeutic target in triple-negative breast cancer

Protein Kinase D1 (PKD1) is a serine/threonine kinase encoded by the PRKD1 gene. PKD1 has been previously shown to be a prognostic factor in ERα+ tamoxifen-resistant breast tumors and PKD1 overexpression confers estrogen independence to ERα+ MCF7 cells. In the present study, our goal was to determin...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Spasojevic, Caroline, Marangoni, Elisabetta, Vacher, Sophie, Assayag, Franck, Meseure, Didier, Château-Joubert, Sophie, Humbert, Martine, Karam, Manale, Ricort, Jean Marc, Auclair, Christian, Regairaz, Marie, Bièche, Ivan
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955414/
https://ncbi.nlm.nih.gov/pubmed/29796183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25292
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