Pin1 facilitates NF-κB activation and promotes tumour progression in human hepatocellular carcinoma

BACKGROUND: NF-κB promotes HCC progression; however, therapies targeting NF-κB are not used due to severe adverse reactions. Pin1 is reported to induce tumour progression in vitro. However, the role of Pin1 in HCC is unclear. Moreover, little is known about the mechanism of Pin1-mediated NF-κB activ...

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發表在:Br J Cancer
Main Authors: Shinoda, Kimio, Kuboki, Satoshi, Shimizu, Hiroaki, Ohtsuka, Masayuki, Kato, Atsushi, Yoshitomi, Hideyuki, Furukawa, Katsunori, Miyazaki, Masaru
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
主題:
Molecular Diagnostics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815797/
https://ncbi.nlm.nih.gov/pubmed/26461058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.272
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