Pin1 facilitates NF-κB activation and promotes tumour progression in human hepatocellular carcinoma

BACKGROUND: NF-κB promotes HCC progression; however, therapies targeting NF-κB are not used due to severe adverse reactions. Pin1 is reported to induce tumour progression in vitro. However, the role of Pin1 in HCC is unclear. Moreover, little is known about the mechanism of Pin1-mediated NF-κB activ...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Shinoda, Kimio, Kuboki, Satoshi, Shimizu, Hiroaki, Ohtsuka, Masayuki, Kato, Atsushi, Yoshitomi, Hideyuki, Furukawa, Katsunori, Miyazaki, Masaru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815797/
https://ncbi.nlm.nih.gov/pubmed/26461058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.272
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