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Pin1 facilitates NF-κB activation and promotes tumour progression in human hepatocellular carcinoma

BACKGROUND: NF-κB promotes HCC progression; however, therapies targeting NF-κB are not used due to severe adverse reactions. Pin1 is reported to induce tumour progression in vitro. However, the role of Pin1 in HCC is unclear. Moreover, little is known about the mechanism of Pin1-mediated NF-κB activ...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Br J Cancer
Κύριοι συγγραφείς: Shinoda, Kimio, Kuboki, Satoshi, Shimizu, Hiroaki, Ohtsuka, Masayuki, Kato, Atsushi, Yoshitomi, Hideyuki, Furukawa, Katsunori, Miyazaki, Masaru
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815797/
https://ncbi.nlm.nih.gov/pubmed/26461058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.272
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