Low-Level Stress Induces Production of Neuroprotective Factors in Wild-Type but Not BDNF(+/-) Mice: Interleukin-10 and Kynurenic Acid

BACKGROUND: Brain-derived neurotrophic factor (BDNF) deficiency confers vulnerability to stress, but the mechanisms are unclear. BDNF(+/-) mice exhibit behavioral, physiological, and neurochemical changes following low-level stress that are hallmarks of major depression. After immune challenge, neur...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Dugan, Allison M., Parrott, Jennifer M., Redus, Laney, Hensler, Julie G., O’Connor, Jason C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815464/
https://ncbi.nlm.nih.gov/pubmed/26232788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv089
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