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Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge

BACKGROUND: Inflammation increases the risk of developing depression-related symptoms, and tryptophan metabolism is an important mediator of these behavior changes. Peripheral immune activation results in central up-regulation of pro-inflammatory cytokine expression, microglia activation, and the pr...

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Bibliografske podrobnosti
izdano v:J Neuroinflammation
Main Authors: Parrott, Jennifer M., Redus, Laney, O’Connor, Jason C.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884395/
https://ncbi.nlm.nih.gov/pubmed/27233247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0590-y
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