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1,3‐propanediol binds deep inside the channel to inhibit water permeation through aquaporins
Aquaporins and aquaglyceroporins (AQPs) are membrane channel proteins responsible for transport of water and for transport of glycerol in addition to water across the cell membrane, respectively. They are expressed throughout the human body and also in other forms of life. Inhibitors of human AQPs h...
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| Veröffentlicht in: | Protein Sci |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4815352/ https://ncbi.nlm.nih.gov/pubmed/26481430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2832 |
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