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1,3‐propanediol binds deep inside the channel to inhibit water permeation through aquaporins

Aquaporins and aquaglyceroporins (AQPs) are membrane channel proteins responsible for transport of water and for transport of glycerol in addition to water across the cell membrane, respectively. They are expressed throughout the human body and also in other forms of life. Inhibitors of human AQPs h...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Yu, Lili, Rodriguez, Roberto A., Chen, L. Laurie, Chen, Liao Y., Perry, George, McHardy, Stanton F., Yeh, Chih‐Ko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815352/
https://ncbi.nlm.nih.gov/pubmed/26481430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2832
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