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Covalent docking using autodock: Two‐point attractor and flexible side chain methods

We describe two methods of automated covalent docking using Autodock4: the two‐point attractor method and the flexible side chain method. Both methods were applied to a training set of 20 diverse protein–ligand covalent complexes, evaluating their reliability in predicting the crystallographic pose...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Bianco, Giulia, Forli, Stefano, Goodsell, David S., Olson, Arthur J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815316/
https://ncbi.nlm.nih.gov/pubmed/26103917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2733
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