Inter-regulation of IGFBP1 and FOXO3a unveils novel mechanism in ursolic acid-inhibited growth of hepatocellular carcinoma cells

BACKGROUND: Ursolic acid (UA), a natural pentacyclic triterpenoid, exerts anti-tumor effects in various cancer types including hepatocellular carcinoma (HCC). However, the molecular mechanisms underlying this remain largely unknown. METHODS: Cell viability and cell cycle were examined by MTT and Flo...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Yang, Li Jun, Tang, Qing, Wu, Jingjing, Chen, Yuqing, Zheng, Fang, Dai, Zhenhui, Hann, Swei Sunny
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815122/
https://ncbi.nlm.nih.gov/pubmed/27036874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0330-2
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