Whole genome sequencing in cats, identifies new models for blindness in AIPL1 and somite segmentation in HES7

BACKGROUND: The reduced cost and improved efficiency of whole genome sequencing (WGS) is drastically improving the development of cats as biomedical models. Persian cats are models for Leber’s congenital amaurosis (LCA), the most severe and earliest onset form of visual impairment in humans. Cats wi...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Lyons, Leslie A., Creighton, Erica K., Alhaddad, Hasan, Beale, Holly C., Grahn, Robert A., Rah, HyungChul, Maggs, David J., Helps, Christopher R., Gandolfi, Barbara
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815086/
https://ncbi.nlm.nih.gov/pubmed/27030474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2595-4
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