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Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome

BACKGROUND: Membrane proteins are key components in a large spectrum of diverse functions and thus account for the major proportion of the drug-targeted portion of the genome. From a structural perspective, the α-helical transmembrane proteins can be categorized into major groups based on the number...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Attwood, Misty M., Krishnan, Arunkumar, Pivotti, Valentina, Yazdi, Samira, Almén, Markus Sällman, Schiöth, Helgi B.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815072/
https://ncbi.nlm.nih.gov/pubmed/27030248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2592-7
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