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The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi

G protein-coupled receptors (GPCRs) in humans are classified into the five main families named Glutamate, Rhodopsin, Adhesion, Frizzled and Secretin according to the GRAFS classification. Previous results show that these mammalian GRAFS families are well represented in the Metazoan lineages, but the...

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Autori principali: Krishnan, Arunkumar, Almén, Markus Sällman, Fredriksson, Robert, Schiöth, Helgi B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251606/
https://ncbi.nlm.nih.gov/pubmed/22238661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029817
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