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An evolutionary roadmap to the microtubule-associated protein MAP Tau

BACKGROUND: The microtubule associated protein Tau (MAPT) promotes assembly and interaction of microtubules with the cytoskeleton, impinging on axonal transport and synaptic plasticity. Its neuronal expression and intrinsic disorder implicate it in some 30 tauopathies such as Alzheimer’s disease and...

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Publicado en:BMC Genomics
Main Authors: Sündermann, Frederik, Fernandez, Maria-Pilar, Morgan, Reginald O.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815063/
https://ncbi.nlm.nih.gov/pubmed/27030133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2590-9
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