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An evolutionary roadmap to the microtubule-associated protein MAP Tau

BACKGROUND: The microtubule associated protein Tau (MAPT) promotes assembly and interaction of microtubules with the cytoskeleton, impinging on axonal transport and synaptic plasticity. Its neuronal expression and intrinsic disorder implicate it in some 30 tauopathies such as Alzheimer’s disease and...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Sündermann, Frederik, Fernandez, Maria-Pilar, Morgan, Reginald O.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815063/
https://ncbi.nlm.nih.gov/pubmed/27030133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2590-9
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