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Update on Pyrin Functions and Mechanisms of Familial Mediterranean Fever

Mutations in the MEFV gene, which encodes the protein named pyrin (also called marenostrin or TRIM20), are associated with the autoinflammatory disease familial Mediterranean fever (FMF). Recent genetic and immunologic studies uncovered novel functions of pyrin and raised several new questions in re...

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Dades bibliogràfiques
Publicat a:Front Microbiol
Autors principals: Manukyan, Gayane, Aminov, Rustam
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815028/
https://ncbi.nlm.nih.gov/pubmed/27066000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00456
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