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Update on Pyrin Functions and Mechanisms of Familial Mediterranean Fever

Mutations in the MEFV gene, which encodes the protein named pyrin (also called marenostrin or TRIM20), are associated with the autoinflammatory disease familial Mediterranean fever (FMF). Recent genetic and immunologic studies uncovered novel functions of pyrin and raised several new questions in re...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Manukyan, Gayane, Aminov, Rustam
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815028/
https://ncbi.nlm.nih.gov/pubmed/27066000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00456
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