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Long range recognition and selection in IDPs: the interactions of the C-terminus of p53
The C-terminal domain of p53 is an extensively studied IDP, interacting with different partners through multiple distinct conformations. To explore the interplay between preformed structural elements and intrinsic fluctuations in its folding and binding we combine extensive atomistic equilibrium and...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814905/ https://ncbi.nlm.nih.gov/pubmed/27030593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23750 |
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