Different effects of antisense RelA p65 and NF-κB1 p50 oligonucleotides on the nuclear factor-κB mediated expression of ICAM-1 in human coronary endothelial and smooth muscle cells

BACKGROUND: Activation of nuclear factor-κB (NF-κB) is one of the key events in early atherosclerosis and restenosis. We hypothesized that tumor necrosis factor-α (TNF-α) induced and NF-κB mediated expression of intercellular adhesion molecule-1 (ICAM-1) can be inhibited by antisense RelA p65 and NF...

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Detalhes bibliográficos
Main Authors: Voisard, Rainer, Huber, Nicola, Baur, Regine, Susa, Milorat, Ickrath, Oliver, Both, Anton, Koenig, Wolfgang, Hombach, Vinzenz
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2001
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC48145/
https://ncbi.nlm.nih.gov/pubmed/11532196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-2-7
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