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Prediction of binding affinity and efficacy of thyroid hormone receptor ligands using QSAR and structure based modeling methods
The thyroid hormone receptor (THR) is an important member of the nuclear receptor family that can be activated by endocrine disrupting chemicals (EDC). Quantitative Structure-Activity Relationship (QSAR) models have been developed to facilitate the prioritization of THR-mediated EDC for the experime...
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| Udgivet i: | Toxicol Appl Pharmacol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814443/ https://ncbi.nlm.nih.gov/pubmed/25058446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.07.009 |
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