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Predicting Drug-induced Hepatotoxicity Using QSAR and Toxicogenomics Approaches

Quantitative Structure-Activity Relationship (QSAR) modeling and toxicogenomics are used independently as predictive tools in toxicology. In this study, we evaluated the power of several statistical models for predicting drug hepatotoxicity in rats using different descriptors of drug molecules, name...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Low, Yen, Uehara, Takeki, Minowa, Yohsuke, Yamada, Hiroshi, Ohno, Yasuo, Urushidani, Tetsuro, Sedykh, Alexander, Muratov, Eugene, Fourches, Denis, Zhu, Hao, Rusyn, Ivan, Tropsha, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281093/
https://ncbi.nlm.nih.gov/pubmed/21699217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200148a
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