Predicting Drug-induced Hepatotoxicity Using QSAR and Toxicogenomics Approaches

Quantitative Structure-Activity Relationship (QSAR) modeling and toxicogenomics are used independently as predictive tools in toxicology. In this study, we evaluated the power of several statistical models for predicting drug hepatotoxicity in rats using different descriptors of drug molecules, name...

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Bibliografski detalji
Izdano u:Chem Res Toxicol
Glavni autori: Low, Yen, Uehara, Takeki, Minowa, Yohsuke, Yamada, Hiroshi, Ohno, Yasuo, Urushidani, Tetsuro, Sedykh, Alexander, Muratov, Eugene, Fourches, Denis, Zhu, Hao, Rusyn, Ivan, Tropsha, Alexander
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281093/
https://ncbi.nlm.nih.gov/pubmed/21699217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200148a
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