Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells

Aberrant Notch signaling has been linked to many cancers including choroid plexus (CP) tumours, a group of rare and predominantly pediatric brain neoplasms. We developed animal models of CP tumours by inducing sustained expression of Notch1 that recapitulate properties of human CP tumours with aberr...

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Bibliographic Details
Published in:Nat Cell Biol
Main Authors: Li, Li, Grausam, Katie B., Wang, Jun, Lun, Melody P., Ohli, Jasmin, Lidov, Hart G. W., Calicchio, Monica L., Zeng, Erliang, Salisbury, Jeffrey L., Wechsler-Reya, Robert J., Lehtinen, Maria K., Schüller, Ulrich, Zhao, Haotian
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814324/
https://ncbi.nlm.nih.gov/pubmed/26999738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3327
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