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Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells
Aberrant Notch signaling has been linked to many cancers including choroid plexus (CP) tumours, a group of rare and predominantly pediatric brain neoplasms. We developed animal models of CP tumours by inducing sustained expression of Notch1 that recapitulate properties of human CP tumours with aberr...
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Gepubliceerd in: | Nat Cell Biol |
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Hoofdauteurs: | , , , , , , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814324/ https://ncbi.nlm.nih.gov/pubmed/26999738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3327 |
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