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PL-02 NOTCH-MEDIATED SUPPRESSION OF MULTICILIATE DIFFERENTIATION PROMOTES CHOROID PLEXUS TUMOR INITIATION FROM EPITHELIAL PROGENITOR IN RESPONSE TO Shh SIGNALS

Choroid plexus (CP) tumors are intraventricular papillary neoplasms mainly found in children. While CP papilloma is a benign tumor, CP carcinoma is malignant and associated with poor prognosis. Though previous studies implicate Notch signaling in CP tumorigenesis, the developmental origin and mechan...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Li, Li, Picotte, Katie, Ohli, Jasmin, Schüller, Ulrich, Zhao, Haotian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218468/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou267.2
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