Specific transport of 3‐fluoro‐l‐α‐methyl‐tyrosine by LAT1 explains its specificity to malignant tumors in imaging

3‐(18)F‐l‐α‐methyl‐tyrosine ([(18)F]FAMT), a PET probe for tumor imaging, has advantages of high cancer‐specificity and lower physiologic background. FAMT‐PET has been proved useful in clinical studies for the prediction of prognosis, the assessment of therapy response and the differentiation of mal...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Wei, Ling, Tominaga, Hideyuki, Ohgaki, Ryuichi, Wiriyasermkul, Pattama, Hagiwara, Kohei, Okuda, Suguru, Kaira, Kyoichi, Oriuchi, Noboru, Nagamori, Shushi, Kanai, Yoshikatsu
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814262/
https://ncbi.nlm.nih.gov/pubmed/26749017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12878
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